Tomato skin extract, naringenin chalcone, shows strong inhibition of histamine release. According to recent research from Japan, "The anti-allergic activity of a tomato extract was studied by using an in vitro histamine-release assay.
The tomato skin extract exerted the strongest inhibition of histamine release. Chlorogenic acid, rutin and naringenin were identified in the 60% ethanol extract of tomato skin."