"We conducted a 7 ±0.5-mo randomized, double-blind, placebo-controlled trial of CLA in 62 prepubertal children aged 6-10 years who were overweight or obese but otherwise healthy. The subjects were randomly assigned to receive 3g/d of 80% CLA (50:50 cis-9,trans-11 and trans-10,cis-12 isomers) or placebo in chocolate milk. Some 53 subjects completed the trial (n=28 in the CLA group, n=25 in the placebo group). CLA attenuated the increase in BMI (0.5 ±0.8) compared with placebo (1.1 ±1.1) (p=0.05).
"The percentage change in body fat measured by dual-energy X-ray absorptiometry was smaller (p=0.001) in the CLA group (-0.5 ±2.1%) than in the placebo group (1.3 ±1.8%). The change in abdominal body fat as a percentage of total body weight was smaller (p=0.02) in the CLA group (-0.09 ±0.9%) than in the placebo group (0.43 ±0.6%). There were no significant changes in plasma glucose, insulin, or LDL cholesterol between groups.