Deerland’s spore-forming probiotic DE111® shown to germinate in the human GI tract
Deerland Probiotics & Enzymes announced the publication of a new study that is the first of its kind to directly investigate the germination of a spore-forming probiotic strain in the human small intestines. The study entitled, “Presence and germination of the probiotic Bacillus subtilis DE111® in the human small intestinal tract,” has been published in Frontiers in Microbiology.
The randomized, crossover, double-blind, placebo-controlled study investigated germination activity of Deerland’s Bacillus subtilis DE111® in 11 individuals with stable ileostomies, which was IRB-approved. An ileostomy involves the disconnection of the small intestine from the colon, and reconnection to an external ileal bag. With access to the contents of the ileal bags, investigators were able to directly examine spore germination under real-time in-vivo conditions in the human small intestine for the first time.