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Guduchi (Tinospora cordifolia) is also known as amrit in Sanskrit, the ancient language of India, where it is associated with longevity. In India, guduchi has been used therapeutically for centuries as a preventative against infections and to maintain good health. It is one of the most valued herbs in Ayurvedic medicine and is widely used to maintain joint health; to preserve normal blood sugar levels; and to enhance the immune system. A recent study demonstrated that traditional uses of guduchi were indeed justified. Guduchi is a climbing shrub with glossy, heart-shaped leaves. It grows throughout India in deciduous and dry forests. The bark is succulent and creamy-white to grey, spotted with large rosette-like lenticels. It has yellow flowers, which gives way to drupes of a cherry-like fruit. All the parts of the plant have therapeutic properties. The leaves are rich in proteins, calcium and phosphorous. An extract from its roots has been used to treat stress, and preliminary studies suggest it could have a positive effect on maintaining healthy blood sugar levels. Its fruit has been used for maintaining joint health, and the stem, high in alkaloids, is the most commonly used part, shown to reduce mucus, protect a healthy liver and have a calming effect on the nervous system. The active compounds in guduchi include alkaloids, diterpenoid lactones, glycosides, steroids, sisquiterpenoid, phenolics, aliphatic compounds and polysaccharides. Clinical studies have shown that the dried stem of guduchi enhanced healing, and a compound preparation was found to reduce the pain of joint conditions. Other research suggests guduchi could help maintain healthy nasal cavities. Preliminary studies suggest it might also help maintain healthy blood glucose levels. NP Nutra Inc. produces a high-quality guduchi P.E. 5% bitters, as well as a straight guduchi powder. Both are suitable for use in various supplement products.