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The study, published in the International Journal of Molecular Sciences on August 2019 was led by Jose Fernandez-Albarral, PhD, of the Complutense University of Madrid, demonstrated the neuroprotective and anti-inflammatory effects of Pharmactive’s proprietary hydrophilic saffron extract (standardized to 3% crocin content) in a mouse model of unilateral, laser-induced ocular hypertension (OHT).