R&D: A New (Old) Ingredient for Bone Health -- June 2008
Isoflavones, the phytochemicals found in soy, are most well-known for their potential to reduce menopausal symptoms and decrease the risk of hormone-related cancers. However, osteoporosis prevention may end up being the crown jewel on the list of isoflavone’s health benefits. The Baby Boomer population is aging, and the National Institute of Health predicts that one out of every two women and one in four men over 50 will suffer a fracture due to osteoporosis in their lifetime.
Two very recent meta-analyses of controlled, clinical trials concluded that soy isoflavone supplementation (90mg/day) significantly inhibits bone resorption, stimulates bone formation and increases spine bone mineral density (BMD) in menopausal women.
Positive results in the studies prompted the USDA to fund the OPUS study (Osteoporosis Prevention Using Soy), a two-year, double-blind, placebo-controlled trial of over 400 post-menopausal women. This study combined the proprietary isoflavone source with 1,000mg of calcium carbonate and 400IUs of vitamin D. The results of the OPUS study were recently presented at the 7th International Soy Symposium and will soon be published in the New England Journal of Medicine. The OPUS study validated the previous research--a significant, protective effect on whole-body bone density can be achieved with daily isoflavone supplementation.
Based on these results, Frutarom has introduced Osteo-Life™, a proprietary blend of SoyLife, calcium carbonate and vitamin D. Laurent Leduc, vice president, business development and marketing for Frutarom USA, explains, “The New Osteo-Life blend was inspired by the OPUS study. This new blend reflects the exact dosage used by the group in the OPUS study showing the highest results.” Osteo-Life and SoyLife can be used in numerous applications, such as cereals, bars, dietary supplements and juices. At the suggested rates of 450mg/day for SoyLife or 1,500mg/day for the Osteo-Life blend, the flavor influence in functional foods is negligible. “Frutarom’s mission has always been to combine healthy and good-tasting solutions to our customers,” adds Leduc. NS
-- Ginny Bank, Contributing Editor
For more information:
Frutarom USA Inc. * North Bergen, N.J.
Jocelyn Mathern, R.D. * 952-920-7700
email@example.com * www.frutarom.com
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5 Pricherit C, et al. 2000. J Nutri. 130:1675-1681.