Nexira has released new human trial data showing the benefit of inavea™ PURE ACACIA on transit modulation and its extreme tolerability on sensitive people with IBS.
According to the results of the Rome Foundational study, it was found that across 33 countries on six continents, more than 40% of persons worldwide suffer with a functional gastrointestinal disorder, such as IBS, and this dramatically affects their quality of life and healthcare use. Across Europe, consumer spending on OTC and supplements is considerable. Diets and supplements have crucial roles in managing these disorders, and brands can play a part. (1)
With more than 40 years of research in gut and microbiome, Nexira continues to complete its expertise and has released new study results on its prebiotic fiber.
As part of the IBSQUtrition project (2017-2022), Wageningen University & Research and its partners has conducted important research on people with irritable bowel syndrome (IBS) using the nutrition.
“Nexira has joined this consortium to learn more about the effect of its acacia fiber on transit,” explained Damien Guillemet, Nexira Scientific Director.
Pre-clinical studies have demonstrated the benefit of inavea™ PURE ACACIA on transit and digestive comfort.
An interventional double-blinded clinical study vs placebo has been realized (publication in progress). inavea™ PURE ACACIA has been evaluated on 120 persons from the predominantly constipated category of IBS people. They have taken 10g of inavea™ PURE ACACIA during four weeks, vs placebo.
inavea™ PURE ACACIA has demonstrated its potency by significantly improving constipation for IBS people.
“It was the first time that acacia fiber has demonstrated its benefit on transit modulation in adults,” said Guillemet.
“Talking about constipation or transit seems to be old fashioned in front of microbiome, -biotics and so on. However, with more than 40% of people worldwide suffering from with a functional gastrointestinal disorder, this solution to improve transit still has a huge potential for supplement manufacturers,” added Julie Impérato, Nexira Marketing manager.
In addition, according to EFSA guidances, this improvement of transit is also valuable for occasional constipation in general population.
A secondary end-point of the study was about the digestive comfort. Nexira has previously demonstrated that acacia fiber is highly tolerable, especially compared to FOS. The interesting point of this latest study is that inavea™ PURE ACACIA was compatible with IBS population, known to be highly sensitive.
Guillemet concludes, “inavea™ supplementation did not trigger higher severity score or symptoms and even tends to decrease them.”
Imperato adds, “One of the most important threats for fiber intake is the associated digestive discomfort. That said, these results supporting the digestive comfort are certainly a major asset for inavea™ PURE ACACIA.”
These new results confirm that inavea™ PURE ACACIA supports transit modulation by improving constipation, with a high digestive comfort. Thanks to its properties, inavea™ PURE ACACIA can be used in a large array of applications, from supplements in powder to functional food and beverage such as trendy carbonates, functional alt-dairy or convenient bars, which open the field of innovation and new concepts.
1 Worldwide Prevalence and Burden of Functional Gastrointestinal Disorders, Results of Rome Foundation Global Study, Sperber et al., 2020
inavea™ PURE ACACIA is an all-natural, organic and GMO-free dietary fiber sourced from carefully selected acacia trees. inavea™ PURE ACACIA offers a carbon neutral footprint and the value of high digestive tolerance for fiber enrichment and prebiotic effect in a large array of applications.
Founded in 1895, Nexira is a global leader in natural and organic ingredients and botanical extracts for the food, nutrition, and dietary supplements industries.
Nexira built its reputation as the world leader in acacia and now manufactures a wide range of natural products with recognized health benefits. Our portfolio of products includes highly functional and nutritional ingredients, antioxidants and active botanicals for digestive health, weight management, stress management, sports nutrition, cognitive health and cardiovascular health. We operate on five continents, with eight subsidiaries, eight manufacturing plants and an extensive network of partners in more than 80 countries.