PL Thomas and Co., Inc. and Polinat S.A. announced publication of a peer-reviewed study about the effects of Xanthigen in the Journal of Agricultural Food Chemistry (2012 Jan 3). This research supports a 2010 published, peer-reviewed clinical paper describing the role of Xanthigen in weight management (Diabetes, Obesity, and Metabolism 12:72-8, 2010). Xanthigen is a patent-pending composition standardized to two synergistic anti-obesity compounds: fucoxanthin (from brown sea weed) and punicic acid (a unique gamma-linolenic acid from pomegranate seed oil). The 2010 published report involved a 16-week, double-blind, randomized, placebo-controlled study with non-diabetic, obese patients. It showed Xanthigen lowered liver fat, body weight and improved liver markers in volunteers with non-alcoholic fatty liver disease (NAFLD), the companies say. The molecular basis of the clinical findings was further investigated in the in vitro study. — P.L. Thomas, www.plthomas.comNS