Deerland Probiotics & Enzymes announced that the United States Patent and Trademark Office has published its application for a distinct use of Deerland’s signature strain DE111® of the probiotic species, Bacillus subtilis DE111® based on compelling human clinicals performed on DE111®.

The patent application (US# 2021-315808 A1) titled “Bacillus subtilis containing composition for treatment of gastrointestinal irregularity” claims the use of B. subtilis strain DE111® for promoting GI and bowel regularity.  Deerland envisions additional applications for supplements and functional foods/beverages claiming anti-fungal and anti-microbial properties that exert health benefits of gastrointestinal regularity, immune support and balancing of the microbiome. 

The application, in part, describes, “As a component of the human microbiome, Bacillus subtilis may potentially have the ability to promote gastrointestinal health, including helping its host in digestion, making Bacillus subtilis a good candidate for probiotic compositions.”

The application summarizes studies of 30, 60 and 90 days in individuals with bowel irregularity who consumed B. subtilis, all resulting in measurable improvements. According to the application’s summary of invention, “the present disclosure relates to a method of [supporting] gastrointestinal irregularity in an individual, wherein the individuals has at least one 24-hour episode per month of bowel movements measuring 1 or 2 on the Bristol Stool Scale.” 

In the Bristol Stool Scale (or chart), out of 7 types, types 1 and 2 are difficult to pass and are indicative of constipation. The Bristol Stool Chart is a widely used tool for physicians to discern lower gastrointestinal function.

Bacillus subtilis is a spore-forming probiotic, which has the ability to protect itself through manufacturing and through digestion. B. subtilis DE111® has more than 30 studies (in vitro and human clinicals) demonstrating its effects on digestive and immune health in adults and children.  

“This patent application underscores the safety and efficacy of B. subtilis, including DE111®,” stated Dr. John Deaton, vice president of science and technology at Deerland. “And it is timely, as according to Allied Market Research, worldwide, bowel irregularity is a common occurrence in up to 32.5% of the global population; and further, bowel irregularity and the discomfort it causes increases with age.”

About Deerland Probiotics & Enzymes
Deerland Probiotics & Enzymes, based in Kennesaw, Georgia, is part of ADM, a global leader in human and animal nutrition and the world’s premier agricultural origination and processing company. Deerland specializes in developing science-backed solutions that benefit microbiome health, using probiotic, prebiotic and enzyme technology, offering a line of unique, clinically validated branded products. Deerland collaborates with customers to develop innovative and often proprietary solutions in the dietary supplement, food and beverage, sports nutrition, and companion animal markets. The company’s manufacturing services include bulk blends, capsules, stick packs and tablets, as well as bottling and labeling. 

To contact Deerland Probiotics & Enzymes, call toll free +1.800.697.8179 or visit