SIRIO Pharma, a global nutraceutical contract development and manufacturing organization, launched its GummiBiotics™ at CPHI Milan for leading nutraceutical and healthcare brands. These innovative gummies are powered by branded, science-backed macrobiotic strains and are designed to support various health benefits. The range includes three vegetarian gummies, each uniquely formulated for specific needs: GummiBiotics Defense to help support immune health, GummiBiotics IBS Ease to alleviate IBS symptoms, and GummiBiotics Lean to aid in abdominal fat burning.

The biotic supplement segment already accounts for a quarter of all supplements sold, surpassing $3 billion in sales in 2023,[1] with the gummy category growing at an average of 14% CAGR since 2020[2]. Consumers are increasingly prioritizing natural health solutions, while also looking for products that combine proven efficacy with enjoyable dose forms.

The GummiBiotics Defense is powered by 500mg of EpiCor® postbiotic per serving – a unique ingredient that has been the focus of numerous clinical trials for immune and gut health – with added Zinc (5mg) to support the normal function of the immune system. It is a first-to-market postbiotic and expected to see rapid sales growth as the only gummy available featuring EpiCor®.

Irritable Bowel Syndrome (IBS) is a common digestive disorder affecting 15% of people worldwide[3], causing symptoms like abdominal pain, bloating, diarrhoea, or constipation, and many consumers are looking for natural products to help manage symptoms. In another first, Sirio has formulated its GummiBiotics IBS Ease with ADM’s proprietary ES1 Postbiotic – which, in clinical studies, is shown to help moderate some symptoms of IBS-D[4] and deliver a reduction in occasional diarrhoea*. The gummy is further enhanced with xylo-oligosaccharides – with a study showing that xylo-oligosaccharides may help comfort diarrhoea-dominant Irritable Bowel Syndrome (IBS-D)[5] – and Calcium which is known to contribute to the normal functioning of digestive enzymes[6].

The third new product to launch is the GummiBiotics Lean which features a specially formulated combination of apple cider vinegar, Vitamin B6 and DE111® probiotic [containing 5bn CFU] – a strain of Bacillus subtilis that is clinically proven to significantly reduce body fat percentage. The gummy’s metabolic action is further enhanced by 500mg of Sirio’s own premium Apple Cider Vinegar Natuful™ Postbiotic. The formulation is market-ready, powered by science-backed microbiomes, and supports healthy body composition.

[1] Informa NBJ: Supplement Business Report, 2024
[2] QY Research: Global Functional Gummies Market Research Report
[3] World Gastroenterology Organisation (WGO), 2023
[4] Participants who consumed ES1 Postbiotic (Heat-treated Bifidobacterium longum CECT 7347) reduced their IBS-SSS score from moderate to mild in 12 weeks
[5] Srivastava S, Basak U, Naghibi M, et al. A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live Bifidobacterium longum CECT 7347 (ES1) and heat-treated Bifidobacterium longum CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome[J]. Gut Microbes, 2024, 16(1): 2338322.
[6] EFSA Claim